Publications

One-Pot Conversion of Benzyl Alcohols to N-Protected Anilines and Alkyl Alcohols to Carbamoyl Azides
Kobayashi, S.* Yamaguchi, R.; Yamamoto, F.; Komori, J.; Sakamoto, H. Kasashima, T.; Adriaenssens, L.; Lear, M. J.*
Eur. J. Org. Chem. 2023, e202300786. DOI: 10.1002/ejoc.202300786

Total Synthesis of Geranyl-Resorcinols Isolated from Mushrooms of GenusHericium

Kobayashi, S.;*

Synthesis 2023, 55, 417-432. DOI: 10.1055/a-1944-9623

(This paper was selected for the cover graphic​.)

Potential Degradation of 4-Methyltetrahydropyran (4-MeTHP) under Oxidation Conditions

Kobayashi, S.;* Tamura, T.

Asian J. Org. Chem. 2021, 10 (10), 2675-2681. DOI: 10.1002/ajoc.202100441

(The art of this paper was selected as a Cover Feature)

Cyclopentyl methyl ether (CPME) and 4-methyltetrahydropyran (4-MeTHP): Basic chemical properties and applications as next generation reaction solvents

Kobayashi, S.*

J. Synth. Org. Chem. Jpn 2021 , 79 (6), 547-557. (in Japanese) DOI: 10.5059 / yukigoseikyokaishi.79.547

Total Synthesis, Structure Revision and Neuroprotective Effect of Hericenones C–H and Their Derivatives

Kobayashi, S .; * Tamura, T .; Koshishiba, M .; Yasumoto, T .; Shimizu, S .; Kintaka, T .; Nagai, K.

J. Org. Chem. 2021 , 86 (3), 2602-2620. DOI: 10.1021 / acs.joc.0c02681

Stereocontrolled Total Synthesis of (+)-Isolaurenidificin and (–)-Bromlaurenidificin

Kobayashi, S .; * Hori, Y .; Yoneyama, R .; Tamura, T .; Masuyama, A.

J. Org. Chem .  2019 , 84 (23), 15549-15556. DOI: 10.1021 / acs.joc.9b02532

4-Methyltetrahydropyran (4-MeTHP): Application as an Organic Reaction Solvent

Kobayashi, S .; * Tamura, T .; Yoshimoto, Y .; Kawakami, T .; Masuyama, A.

Chem. Asian J.  2019 , 14 (21), 3921-3937. DOI: 10.1002 / asia.201901169

(This paper was selected for a special collection celebrating 100th Annual Meeting of CSJ)

Total syntheses and endoplasmic reticulum stress suppressive activities of hericenes A−C and their derivatives

Kobayashi, S .; * Hamada, Y .; Yasumoto, T .; Hashino, Y .; Masuyama, A .; Nagai, K. *

Tetrahedron Lett .  2018 , 59 (18), 1733-1736. DOI: 10.1016 / j.tetlet.2018.03.065

Syntheses of (−)-Tripterifordin and (−)-Neotripterifordin from Stevioside

Kobayashi, S .; * Shibukawa, K .; Hamada, Y .; Kuruma, T .; Kawabata, A .; Masuyama, A.

J. Org. Chem .  2018 , 83 (3), 1606-1613. DOI: 10.1021 / acs.joc.7b02916

Grignard Reactions in Cyclopentyl Methyl Ether (CPME)

Kobayashi, S .; * Shibukawa, K .; Miyaguchi, Y .; Masuyama, A.

Asian J. Org. Chem . 2016 , 5 (5), 636-645. DOI: 10.1002 / ajoc.201600059

(Most Accessed 07/2020 to 06/2021) 

Stereocontrolled Synthesis of a Possible Stereoisomer of Laurenidificin and a Formal Total Synthesis of (+)-Aplysiallene Featuring a Stereospecific Ring Contraction

Kobayashi, S .; * Yokoi, T .; Inoue, T .; Hori, Y .; Saka, T .; Shimomura, T .; Masuyama, A.

J. Org. Chem . 2016 , 81 (4), 1484-1498. DOI: 10.1021 / acs.joc.5b02595

Divergent Total Synthesis of Bioactive Molecules Derived from the Fruiting Bodies of Hericium erinaceum

Kobayashi, S.*

J. Synth. Org. Chem. Jpn 2015 , 73 (2), 131-139. (in Japanese)

DOI: 10.5059 / yukigoseikyokaishi.73.131

Divergent Synthesis of Bioactive Resorcinols Isolated from the Fruiting Bodies of Hericium erinaceum: Total Syntheses of Hericenones A, B and I, Hericenols BD, and Erinacerins A and B

Kobayashi, S .; * Tamanoi, H .; Hasegawa, Y .; Segawa, Y .; Masuyama, A.

J. Org. Chem . 2014 , 79 (11), 5227-5238. DOI: 10.1021 / jo500795z

Evaluation of Cyclopentyl Methyl Ether (CPME) as a Solvent for Radical Reactions

Kobayashi, S .; * Kuroda, H .; Ohtsuka, Y .; Kashihara, T .; Masuyama, A .; Watanabe, K.

Tetrahedron 2013 , 69 (10), 2251-2259. DOI: 10.1016 / j.tet.2013.01.030

Total Synthesis and Structural Revision of Hericerin

Kobayashi, S .; * Inoue, T .; Ando, A .; Tamanoi, H .; Ryu, I .; Masuyama, A.

J. Org. Chem . 2012 , 77 (13), 5819-5822. DOI: 10.1021 / jo300719m

Rapid Access to 6-Bromo-5,7-dihydroxyphthalide 5-Methyl Ether by a CuBr2-Mediated Multi-Step Reaction. Concise Total Syntheses of Hericenone J and 5'-Deoxohericenone C (Hericene A)

Kobayashi, S .; * Ando, A .; Kuroda, H .; Ejima, S .; Masuyama, A .; Ryu, I.

Tetrahedron 2011 , 67 (47), 9087-9092. DOI: 10.1016 / j.tet.2011.09.104

Stereocontrolled Synthesis of Substituted Bicyclic Ethers through Oxy-Favorskii Rearrangement. Total Synthesis of (±)-Communiol E

Kobayashi, S .; * Kinoshita, T .; Kawamoto, T .; Wada, M .; Kuroda, H .; Masuyama, A .; Ryu, I.

J. Org. Chem . 2011 , 76 (17), 7096-7103. DOI: 10.1021 / jo201064h

(This article was featured in Synfacts 2011 , 11 , 1160.)

Black Light Induced Radical Hydroxymethylation of Alkyl Iodides with Atmospheric CO in the Presence of Tetrabutylammonium Borohydride

Kobayashi, S .; Kawamoto, T .; Uehara, S .; Fukuyama, T .; Ryu, I. *

Org. Lett . 2010 , 12 (7), 1548-1551. DOI: 10.1021 / ol1002847

Novel Radical Cyclization Method Accompanied by Elimination of Hydrazyl Radical

Kobayashi, S .; Hirao, H .; Kawauchi, T .; Ryu, I. *

Heterocycles 2010 , 80 (2), 879-885. DOI: 10.3987 / COM-09-S (S) 115

Organocatalytic Enantioselective Synthesis of Nitrogen-Substituted Dihydropyran-2-one, A Key Synthetic Intermediate of 1β-Methylcarbapenems

Kobayashi, S .; * Uehara, H .; Kinoshita, T .; Sudo, T .; Ryu, I.

Org. Lett . 2009 , 11 (17), 3934-3937. DOI: 10.1021 / ol901544q

Enantioselective Synthesis of the Fully Functionalized ABC ring of Zoanthenol

Sugano, N .; Koizumi, Y .; Hirai, G .; Oguri, H .; Kobayashi, S .; Yamashita, S .; Hirama, M. *

Chem. Asian J. 2008 , 3 (8-9), 1549-1557. DOI: 10.1002 / asia.200800079

Construction of the CDE-Ring Framework of Erinacine E through Pummerer-type Cyclization

Kobayashi, S .; * Ishii, A .; Toyota, M.

Synlett 2008 , (7), 1086-1090. DOI: 10.1055 / s-2008-1042922

Synthesis of trans -Fused Tetrahydrooxepins: Stereoselective Allylation of Sulfur or Fluoro-substituted Tetrahydrooxepins

Kobayashi, S .; * Hori, M .; Hirama, M.

Carbohydr. Res . 2008 , 343 (3), 443-452. DOI: 10.1016 / j.carres. 2007.11.018

Radical chain reactions using THP as a solvent

Yasuda, H .; * Uenoyama, Y .; Nobuta, O .; Kobayashi, S .; Ryu, I. *

Tetrahedron Lett . 2008 , 49 (2), 367-370. DOI: 10.1016 / j.tetlet. 2007.11.039

Formal Total Synthesis of Neocarzinostatin Chromophore

Kobayashi, S .; * Hori, M .; Wang, GX; Hirama, M. *

J. Org. Chem . 2006 , 71 (2), 636-644. DOI: 10.1021 / jo052031o

Stereocontrolled Synthesis of the ABCDE Ring Moiety of Ciguatoxin CTX3C

Kobayashi, S .; Takahashi, Y .; Komano, K .; Alizadeh, BH, Kawada, Y .; Oishi, T .; Tanaka, S .; Ogasawara, Y .; Sasaki, S .; Hirama, M. *

Tetrahedron 2004 , 60 (38), 8375-8396. DOI: 10.1016 / j.tet.2004.07.010

Total Synthesisof 9-Membered Enediyne Antibiotic N1999-A2: Absolute Stereochemistry and DNA Cleavage

Kobayashi, S.; * Hirama, M. *

J. Synth. Org. Chem. Jpn 2004 , 62 (3), 184-193. (in Japanese)

DOI: 10.5059 / yukigoseikyokaishi.62.184

Synthesis of the Fully Functionalized ABCDE Ring Moiety of Ciguatoxin

Kobayashi, S .; Alizadeh, BH; Sasaki, S .; Oguri, H .; Hirama, M. *

Org. Lett. 2004 , 6 (5), 751-754. DOI: 10.1021 / ol0364475

Diastereoselective Additions of Ethynyl Grignard Reagent to Erythrulose Derivatives

Kobayashi, S .; Das, P .; Wang, GX; Mita, T .; Lear, MJ; Hirama, M. *

Chem. Lett . 2002 , (3), 300-301. DOI: 10.1246 / cl.2002.300

The First Total Synthesis of N1999-A2: Absolute Stereochemistry and Stereochemical Implications into DNA Cleavage

Kobayashi, S .; Ashizawa, S .; Takahashi, Y .; Sugiura, Y .; Nagaoka, M .; Lear, MJ; Hirama, M. *

J. Am Chem. Soc . 2001 , 123 (45), 11294-11295. DOI: 10.1021 / ja003982g

Investigation of the Total Synthesis of N1999-A2: Implication of Stereochemistry

Kobayashi, S .; Reddy, RS; Sugiura, Y .; Sasaki, D .; Miyagawa, N .; Hirama, M. *

J. Am Chem. Soc . 2001 , 123 (12), 2887-2888. DOI: 10.1021 / ja011779v

Palladium-Catalyzed Coupling of Alkenyl Iodides with Ethynyl Oxiranes: Synthesis of Epoxy Enediyne Core Intermediates Related to Neocarzinostatin Chromophore

Reddy, RS; Iguchi, S .; Kobayashi, S .; Hirama, M. *

Tetrahedron Lett . 1996 , 37 (52), 9335-9336. DOI: 10.1016 / S0040-4039 (97) 82957-7