Natural Product Chemistry Lab
Department of Applied Chemistry Faculty of Engineering, Osaka Institute of Technology
The Latest News
Latest News
Award Ceremony and Lecture of The 19th Society of Synthetic Organic Chemistry Kansai Region Awards were held!
November 11, 2021
November 9th, award ceremony and lecture of the 19th Society of Synthetic Organic Chemistry Kansai Region Awards were held.
Award-winning research title:
Research on divergent total synthesis of biologically active natural products and environmentally benign organic synthesis methods focusing on solvents
The photos of ceremony and lecture are posted on the Blog, so please have a look if you have time.
A research article was published in the November issue of AgriBio!
November 1, 2021
A research article was published in the "Researcher's Square" section of the November issue of Agribio published by Hokuryukan.
Article title:
" Development of neuroprotective agents effective for prevention and improvement of cognitive disorder "
The article introduces chemical approaches to component analyses of mushrooms and efforts toward the development of neuroprotective agents based on structure-activity relationships.
A paper on the oxidative degradation of 4-MeTHP, a hydrophobic ether solvent, has been published!
August 19, 2021
"Potential Degradation of 4-Methyltetrahydropyran (4-MeTHP) under Oxidation Conditions" was published in Asian Journal of Organic Chemistry.
Oxidative degradation mechanism of 4-MeTHP, the new ethereal solvent widely applicable in organic reactions, was surveyed in detail. The image picture of the paper was accepted as Cover Feature in Vol. 10.
A full paper on recyclable ether solvents, CPME and 4-MeTHP has been published!
June 10, 2021
"Cyclopentyl methyl ether (CPME) and 4-methyltetrahydropyran (4-MeTHP): Basic chemical properties and applications as next generation reaction solvents" was published in the June issue of the Journal of Synthetic Organic Chemistry Japan.
This is a review article that summarizes the recyclable hydrophobic ether solvents, CPME and 4-MeTHP, developed by Japanese companies. The paper would be particularly useful for process chemists, who require green chemistry perspectives
J. Synth. Org. Chem. Jpn 2021 , 79 (6), 547-557.
Click here for an introductory article from Chem-Station
A full paper on total synthesis, structure determination, and neuroprotective effects of active ingredients isolated from Lion's mane mushroom has been published!
August 12, 2021
"Total Synthesis, Structure Revision and Neuroprotective Effect of Hericenones C-H and Their Derivatives" was published in The Journal of Organic Chemistry.
This is a full paper that summarizes natural product chemistry research by synthetic organic chemists including total synthesis, structure determination (revision), chemical demonstration of biosynthetic pathway, structure-activity relationship on neuroprotective effect, of active ingredients (hericenones) isolated from edible mushroom Yamabushitake.
One-Pot Conversion of Benzyl Alcohols to N-Protected Anilines and Alkyl Alcohols to Carbamoyl Azides
November 11, 2021
On Tuesday, November 9th, the 19th (2021) Kansai Branch Award Ceremony and Award-Winning Lecture were held.
Award-winning research title:
Research on the comprehensive total synthesis of diverse bioactive natural products and environmentally friendly organic synthesis methods focusing on solvents.
I've written about what happened that day on my blog , so please take a look if you have time.
My research article was published in the November issue of AgriBio!
November 1, 2021
北隆館が出版するアグリバイオ11月号の「研究者の広場」のコーナーで研究記事が掲載されました。
記事のタイトル：
"認知症の予防・改善に資する神経保護薬の創製"
有機合成を基点とするキノコの成分解析へのアプローチや構造活性相関に基づいた神経保護薬の創製に向けた取り組みを紹介しています。