Potential Degradation of 4-Methyltetrahydropyran (4-MeTHP) under Oxidation Conditions

4-Methyltetrahydropyran (4-MeTHP) is a next-generation recyclable ether solvent that can be applied to a wide variety of synthetic reaction methods. Previous studies indicated that 4-MeTHP could degrade to some extent with certain oxidants, while the oxidation reactions themselves proceeded in good yields. Here we disclose the potential oxidative degradation pathways of 4-MeTHP when exposed to selected organic-based and metal-based oxidants. [Open Access]